Similar to Vioxx, Celebrex is a COX-2 inhibitor belonging to the drug class nonsteroidal anti-inflammatory drug (NSAID). Like Vioxx, Celebrex was approved by the Food and Drug Administration (FDA) for the relief of pain and inflammation of osteoarthritis (OA) and rheumatoid arthritis (RA), as well as management of acute pain in adults and primary dysmenorrhea (painful menstrual cramping). And, like Vioxx, Celebrex provides pain relief by inhibiting the COX-2 form of the COX enzyme to block production of prostaglandins. Prostaglandins are hormone-like substances that contribute to the symptoms of pain, fever and inflammation.
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