Vioxx
Vioxx was marketed by Mrck & Co. to treat osteoarthritis, acute pain conditions and dysmenorrhoea. On September 30, 2004 Merck voluntarily withdrew Vioxx from the market because of concerns about increased risk of heart attack and stroke associated with long-term, high-dosage use.
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Frequently Asked Questions
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What is Vioxx?
Vioxx (rofecoxib) is a prescription COX-2 inhibitor nonsteroidal anti-inflammatory drug (NSAID). Vioxx works by inhibiting the COX-2 form of the COX enzyme to block production of prostaglandins. … more -
What is the COX enzyme?
The cyclooxygenase (COX) enzyme has two forms: COX-1 and COX-2. COX-1 is found in a lot of cells all the time, notably the lining of the stomach where it regulates acid production. COX-2 is not … more -
Why has Vioxx been withdrawn from the market?
New research shows that a major Vioxx side effect is a greatly increased risk of cardiovascular (CV) events such as heart attack or stroke if used long-term. more
Legal Articles
- Dangerous Drugs and Product Liability Law
It is difficult for a consumer to adequately assess the safety of a drug before taking it based on limited knowledge. Instead we rely on others such as drug manufacturers, distributors, doctors and pharmacists to help us make the right decision regarding pharmaceutical drugs. While many drugs do what they are intended to do and help relieve our pain or improve our health, some drugs … more - Defective Drug Warning Labels and Off-Label Use
When doctors prescribe drugs they usually take great care to explain the potential side effects you may experience. These warnings are repeated by a pharmacist when you pick up your drugs, and persist on the lengthy warnings labels included with every prescription. These warning labels have been approved by the FDA, often after years of rigorous trials and testing. Drug companies can spend … more
